| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 22/10/26 16:30 | Kairat Almaty | Panathinaikos Athènes | 1-5 |
| 22/10/26 18:45 | FC Nordsjaelland | ZSKA Sofia | 2-2 |
| 22/10/26 18:45 | FK Jablonec | Brighton and Hove Albion | 0-0 |
| 22/10/26 18:45 | FC Getafe | FC Lugano | 2-5 |
| 22/10/26 18:45 | Trabzonspor | Heart of Midlothian | 2-0 |
| 22/10/26 18:45 | Etoile Rouge Belgrade | FC Copenhague | 2-2 |
| 22/10/26 18:45 | FC Iberia 1999 | Mjaellby AIF | 1-1 |
| 22/10/26 18:45 | FK Kauno Zalgiris | Brann Bergen | 1-4 |
| 22/10/26 18:45 | Inter Escaldes | Universitatea Craiova | 1-3 |
| 22/10/26 18:45 | Pafos FC | Riga FC | 1-1 |
| 22/10/26 21:00 | Lincoln Red Imps FC | FC Twente Enschede | 1-4 |
| 22/10/26 21:00 | FK Borac | Kuopion PS | 2-0 |
| 22/10/26 21:00 | FC Midtjylland | Sint-Truidense VV | 0-1 |
| 22/10/26 21:00 | AS Monaco | SC Freiburg | 3-0 |
| 22/10/26 21:00 | Ajax Amsterdam | Atalanta Bergamo | 2-0 |
| 22/10/26 21:00 | Sporting Braga | La Gantoise | 2-0 |
| 22/10/26 21:00 | Aarhus GF | KF Egnatia | 1-1 |
| 22/10/26 21:00 | FC Thun | HNK Hajduk Split | 0-1 |