| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 23/10/25 18:45 | AZ Alkmaar | SK Slovan Bratislava | 1-0 |
| 23/10/25 18:45 | Shakhtar Donetsk | Legia Warschau | 1-2 |
| 23/10/25 18:45 | Racing Club Strasbourg | Jagiellonia Bialystok | 1-1 |
| 23/10/25 18:45 | AEK Athènes | FC Aberdeen | 6-0 |
| 23/10/25 18:45 | Breidablik Kopavogur | Kuopion PS | 0-0 |
| 23/10/25 18:45 | KF Shkendija | FC Shelbourne | 1-0 |
| 23/10/25 18:45 | BK Häcken | Rayo Vallecano | 2-2 |
| 23/10/25 18:45 | KF Drita Gjilan | Omonia Nicosia | 1-1 |
| 23/10/25 18:45 | SK Rapid Wien | AC Florenz | 0-3 |
| 23/10/25 21:00 | Crystal Palace | AEK Larnaka | 0-1 |
| 23/10/25 21:00 | Shamrock Rovers | NK Celje | 0-2 |
| 23/10/25 21:00 | FSV Mayence 05 | HŠK Zrinjski Mostar | 1-0 |
| 23/10/25 21:00 | Lincoln Red Imps FC | Lech Poznan | 2-1 |
| 23/10/25 21:00 | Sigma Olomouc | KS Rakow Czestochowa | 1-1 |
| 23/10/25 21:00 | Samsunspor | Dynamo Kiew | 3-0 |
| 23/10/25 21:00 | Universitatea Craiova | FC Noah | 1-1 |
| 23/10/25 21:00 | Hamrun Spartans | FC Lausanne-Sport | 0-1 |
| 24/10/25 16:00 | HNK Rijeka | Sparta Prag | 1-0 |